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Is there a link between periodontal disease and coronary heart disease?

Identifieur interne : 000562 ( Main/Exploration ); précédent : 000561; suivant : 000563

Is there a link between periodontal disease and coronary heart disease?

Auteurs : R A Seymour ; J G Steele

Source :

RBID : pubmed:9479812

Descripteurs français

English descriptors

Abstract

OBJECTIVE

To provide a critical review of the studies completed to date that have investigated a link between coronary heart disease and dental health.

DESIGN

Retrospective analysis.

SETTING

Mainly hospital-based patients or subjects involved in longitudinal health care studies.

MAIN OUTCOME MEASURES

The incidence of coronary heart disease and its relationship to dental health and other recognised risk factors.

RESULTS

Evidence suggests that dental health, in particular periodontal disease, may be a significant risk factor for coronary heart disease and further coronary events. Possible biological mechanisms that link the two diseases are appraised.

CONCLUSIONS

There does appear to be increasing evidence that a relationship exists between dental health and coronary heart disease, especially in males aged 40-50 years. The presence of a hyperinflammatory monocyte phenotype may provide a common biological mechanism that links the two diseases.


DOI: 10.1038/sj.bdj.4809536
PubMed: 9479812


Affiliations:


Links toward previous steps (curation, corpus...)


Le document en format XML

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<term>Cerebrovascular Disorders (epidemiology)</term>
<term>Cerebrovascular Disorders (physiopathology)</term>
<term>Coronary Disease (epidemiology)</term>
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<term>Gram-Negative Bacteria (physiology)</term>
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<term>Humans (MeSH)</term>
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<term>Inflammation Mediators (metabolism)</term>
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<term>Longitudinal Studies (MeSH)</term>
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<term>Thromboembolism (epidemiology)</term>
<term>Thromboembolism (physiopathology)</term>
<term>Tooth Extraction (MeSH)</term>
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<term>Adulte (MeSH)</term>
<term>Adulte d'âge moyen (MeSH)</term>
<term>Angiopathies intracrâniennes (physiopathologie)</term>
<term>Angiopathies intracrâniennes (épidémiologie)</term>
<term>Bactéries à Gram négatif (physiologie)</term>
<term>Biologie (MeSH)</term>
<term>Causalité (MeSH)</term>
<term>Extraction dentaire (MeSH)</term>
<term>Facteurs de risque (MeSH)</term>
<term>Facteurs sexuels (MeSH)</term>
<term>Facteurs âges (MeSH)</term>
<term>Femelle (MeSH)</term>
<term>Foyer infectieux dentaire (physiopathologie)</term>
<term>Foyer infectieux dentaire (épidémiologie)</term>
<term>Humains (MeSH)</term>
<term>Hémostase (physiologie)</term>
<term>Incidence (MeSH)</term>
<term>Maladie coronarienne (physiopathologie)</term>
<term>Maladie coronarienne (épidémiologie)</term>
<term>Maladies parodontales (physiopathologie)</term>
<term>Maladies parodontales (épidémiologie)</term>
<term>Monocytes (métabolisme)</term>
<term>Monocytes (physiologie)</term>
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<term>Relations dentiste-patient (MeSH)</term>
<term>Responsabilité légale (MeSH)</term>
<term>Sujet âgé (MeSH)</term>
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<term>Thromboembolie (épidémiologie)</term>
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<term>Coronary Disease</term>
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<term>Periodontal Diseases</term>
<term>Thromboembolism</term>
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<term>Maladies parodontales</term>
<term>Thromboembolie</term>
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<term>Coronary Disease</term>
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<term>Thromboembolism</term>
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<term>Angiopathies intracrâniennes</term>
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<b>OBJECTIVE</b>
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<p>To provide a critical review of the studies completed to date that have investigated a link between coronary heart disease and dental health.</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>DESIGN</b>
</p>
<p>Retrospective analysis.</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>SETTING</b>
</p>
<p>Mainly hospital-based patients or subjects involved in longitudinal health care studies.</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>MAIN OUTCOME MEASURES</b>
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<p>The incidence of coronary heart disease and its relationship to dental health and other recognised risk factors.</p>
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<div type="abstract" xml:lang="en">
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<b>RESULTS</b>
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<p>Evidence suggests that dental health, in particular periodontal disease, may be a significant risk factor for coronary heart disease and further coronary events. Possible biological mechanisms that link the two diseases are appraised.</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>CONCLUSIONS</b>
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<p>There does appear to be increasing evidence that a relationship exists between dental health and coronary heart disease, especially in males aged 40-50 years. The presence of a hyperinflammatory monocyte phenotype may provide a common biological mechanism that links the two diseases.</p>
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